Engineering (i.e. Engineering) of Biological Systems
By transferring single genes into suitable hosts, genetic engineering has enabled a remarkable transformation of the pharmaceutical and chemical industry. Nevertheless, complex biological systems such as cells are capable of much more involved tasks, such as multi-signal integration and the coordination of chemical sequences of dozens of steps. The successful programming of cells to accomplish such complex tasks requires reconsideration of the way how we go about the biological engineering process. Are the elements we use for biological systems engineering actually suitable? Are the cells that receive our designs capable of faithful execution? Usually, complexity interferes with the design of artificial systems. However, novel engineering strategies towards the long-term goal of fully predictable systems are emerging, ranging from metabolic channeling to proteomic switching.
Sven Panke ist Professor für Bioverfahrenstechnik an der ETH Zürich.
Ort: Vortragssaal des CAS
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