Vortrag von Prof. Dr. Victor de Lorenzo – Forward Design of Lifesystems: From Genetic Engineering to Synthetic Biology
The early recombinant DNA technology of the late 1970s included the notion of Genetic Engineering as metaphor of how the new methods would allow building new properties in biological systems. Synthetic Biology converts such a seminal engineering analogy into a veritable methodology by overcoming trial-and-error approaches, and setting out to reshape life systems on the basis of a rational blueprint. To this end, biological objects are seen as wholes of stand-alone parts hierarchically assembled in modules, devices, subsystems, and systems that can be abstracted and completely understood. By the same token, the components of extant biological systems can be de-constructed and rationally reconstructed to build new biological objects with properties à la carte. This extreme engineering scene embodies the most extraordinary potential for both understanding the functioning of life systems and for constructing biological materials with a large variety of applications, some of which will be addressed in detail.
Victor de Lorenzo ist Professor für molekulare Umweltmikrobiologie am Centro Nacional de Biotecnología in Madrid.
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